Originally, we could see when initial data were coming out at the planned interim analysis that there was a significant improvement in sCR with the quadruplet [regimen of daratumumab (Darzalex), lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Dara-VRd)] compared with the triplet regimen [RVd].1 We received the final analysis here at IMS 2022. Corporate and Business LawDoty Barlow Britt & Theiman LLP. Marie E. Pinizzotto, M.D., MBA, is currently the President and CEO of the Carol A. Ammon Foundation, a foundation focused on health care and education. Before Frequency, David was President and Chief Executive Officer of Entrega Bio, a PureTech Health-founded biotechnology company focused on oral drug delivery technology. 4-time marathon, 10+ half marathon, and 5-time ultramarathon finisher, A block of Wisconsin Cheddar cheese from a trail 15k. Over 30 advocacy leaders of myeloma patient organizations from 30 countries will be in attendance to share best This video provides information on laboratory tests that myeloma patients may undergo. SOHO 2023 Annual Meeting-Hybrid Vous devez activer le JavaScript pour la visualiser. Chromosome analysis (cytogenetic testing by either karyotyping or FISH). Costa LJ, Chhabra S, Callander NS, et al. He was Chairman and CEO for 16 years. elems["ts"] = JSON.stringify(new Date().getTime()); Her additional accomplishments include successfully climbing Mt. He began his law career in Los Angeles with the firm of Manatt Phelps & Phillips, LLP before returning to the Bay Area in 1988. These patients underwent induction followed by autologous stem cell transplant followed by consolidation. var elems = JSON.parse(jQuery(".corporate-connections").find("input[name='captcha_settings']").val()); Norwalk, CT 06851, The MMRF is a registered 501(c)(3) non-profit. In high-risk patients, the teaching has been that we always need a proteasome inhibitor based on the data from the HOVON-65/GMMG-HD4 trial.8 Patients who got bortezomib-based induction and maintenance, especially if they were high risk with deletion 17p or translocation, had outcomes that were just as good as standard risk patients. Clinical Lymphoma Myeloma and Leukemia - ScienceDirect Recognized for her excellence in myeloma research, Dr. Mateos received the Brian G.M. She has a BS in Economics and Accounting from the University at Albany and her CPA. Prior to co-founding Genomic Health in 2000, Steve served for 14 years in various roles in Discovery Research and Medical Affairs at Genentech, Inc., a biotechnology company dedicated to using human genetic information to discover, develop, manufacture and commercialize medicines to treat patients with serious or life-threatening medical conditions. Earlier in his career, he was a bond trader and founded the Mortgage Finance Group. Kathy received the Open Science Champion of Change award by the White House. Mr. McDougall is Partner at PricewaterhouseCoopers Health Sciences Practice, where he provides services to academic medical centers, bioscience companies, pharmaceutical companies, research universities, colleges, health systems, and other research organizations. International Myeloma Society Annual Meeting Prior to the University of Miami, she worked as a patient navigator with Cardinal Health to help patients close the gaps between their care and treatment. Stable disease is the goal for many of these patients because it means you can go on to the next study or go long enough until the next drug gets approved. Ms. Andrews graduated cum laude from the University of Vermont with a Bachelor of Science degree in biology and earned her law degree, cum laude, from Temple School of Law. Dedicated to optimizing cancer treatment outcomes and bringing the patient voice into product development, Steve Shak, M.D. Daratumumab in combination with bortezomib, thalidomide, and dexamethasone demonstrated benefit compared with VTd alone in subgroup analyses of patients with high-risk multiple myeloma from the phase III CASSIOPEIA trial. He is a Fellow of the American College of Physicians and the American College of Medical Informatics, and an executive board member of the American Medical Informatics Association. Prior to joining SAC, Tom was President of Investment Management Services, Inc (IMS) from 1996 to 1999. He is determined to continue his active hobbies. WebMultiple MyelomaTypes Plasma cell dyscrasias PCL-like MM Transplant-ineligible MM Chromosomal aberrations Risk MM-related mutations View all Types VIEW ALL var response = document.getElementById("g-recaptcha-response-2"); Interested in becoming a supporter? Knowledge is power. Before joining IQVIA, Michael worked at Fuld & Company, a boutique consulting firm specializing in competitive intelligence and strategy, and prior to that, at Siemens Healthcare Diagnostics in the Global Technical Operations group where he resolved technical issues for immunoassay reagents and systems. Recognized for her excellence in myeloma research, Dr. Mateos received the Brian G.M. He has also served as an advisor for Harvard Business School's Kraft Precision Medicine program, using his experience with direct-to-consumer teams to help nonprofits accelerate precision medicine efforts via direct-to-patient engagement. She has persevered and embraces the changes that her diagnosis has caused in her life. Kristen has been a registered nurse for a little over 20 years. Abstract Despite recent advances, multiple myeloma remains an incurable disease for most patients, and initial remission will be followed by relapses requiring therapy. In some of the updates that have been provided at conferences, weve seen that there is a difference in how patients do when they have higher-risk vs standard-risk disease. Donec ullamcorper nulla non metus auctor fringilla. Before and after his diagnosis, he has continued to participate in his hobbies as a marathon runner, hunter, fisherman, and hiker. Prior to the MMRF, Mr. Giusti worked as a Chief Executive Officer, leader, executive and entrepreneur for over 30 years; he has founded, managed and led a variety of businesses. Triplet therapy, transplantation, and maintenance until progression in myeloma. He began his career with Arthur Anderson LLP in the Assurance and Business Advisory Services Division. Susan Marvin, Chair of the Board of The Marvin Companies, was part of the third-generation management team in what is today a fourth-generation family owned and operated company. Voorhees PM, Kaufman JL, Laubach J, et al. Prior to her career in nursing, she worked in marketing and advertising in the real estate industry for 4 years. In 2005, Tricia was dealing with extreme fatigue. Dana earned a BS from Washington and Lee University and an MBA from Harvard Business School. Mr. Giusti holds a Bachelor of Science degree from the Colorado School of Mines and an MBA from Harvard University. Cette adresse e-mail est protge contre les robots spammeurs. Treating Relapsed/Refractory Multiple Myeloma When Three Prior Treatment Lines Fail, Program Chair Robert Z. Orlowski MD, PhD Elisabeth E. Manansanch, MD, 2-M<3.5mg/L and albumin 3.5 g/dL and Im so appreciative of the help weve received, and Im grateful for this opportunity because we understand how this journey with multiple myeloma can be overwhelming. James J. Driscoll, MD, PhD, and James Ignatz-Hoover, MD, PhD, share a perspective on a study published recently in ONCOLOGY. Upon request, we will provide you with information about whether we hold any of your Personal Data along with any details required to be provided to you under applicable law. The combination of melflufen and dexamethasone showed antitumor activity in patients with relapsed or refractory multiple myeloma, both in those with and those without extramedullary disease, according to data from the phase II HORIZON study presented at the 17th International Myeloma Workshop. No significant survival differences were shown between 2 high-dose regimens for newly diagnosed multiple myeloma. In 1969, he joined Edward D. Jones & Co. in Saint Louis and later became a partner. He resides in Irvington, NY with his wife and two sons. Registration:https://www.eventcreate.com/e/fda-imsjointsymposium, More Meetings, She had her first relapse in January of 2021, which was unexpected. Simon J. Harrison, MD, gives key takeaways from his presentation on the ICARIA-MM study, which he recently presented at the 2019 International Myeloma Workshop.
Silbermann: The MASTER design was adjusted during the trial and there was an enrichment to include patients with several high-risk cytogenetic abnormalities. Initially Diagnosed: 2013 Manager, Events & Partnerships, Tia Dawson - Sr. Michael Reinert is a leading music industry attorney who most recently served as Executive Vice President of Business & Legal Affairs for the Universal Motown Republic Group, a division of UMG Recordings, Inc. He lives in the Bay Area with his wife, Marie, the former Mayor of Alameda, CA, and has two adult children (Anthony and Nicole). Anderson: We dont know the criteria for who would benefit the most from transplant vs not. Register Now. Named the Fastest Growing Company in Silicon Valley in 2001, ONI was sold to Ciena in 2002; Hugh then served as a consultant to Ciena. It wasnt until 2014 that she was diagnosed with active Multiple Myeloma. We cannot prevent others from using such data in a manner that may violate these Disclosures, the law, or your personal privacy and safety. CARTITUDE-2: Ciltacabtagene autoleucel in patients with progressive multiple Prof Adam Cohen - University of Pennsylvania, Philadelphia, USA. Autologous Stem Cell Transplantation (ACST), Friday, May 5, 2023, 1:00 PM-2:00 PM (ET), Multiple Myeloma Precursor Conditions, With Updates, Wednesday, April 5, 2023, 2:30 PM-3:30 PM (ET), BCMA-Targeted Bispecific Antibodies in Multiple Myeloma, Tuesday, March 21, 2023, 4:00 PM-5:00 PM (ET), Management of Patients Who Have Relapsed After One to Three Prior Lines of Therapy, With Updates, Wednesday, March 8, 2023, 1:00 PM-2:00 PM (ET), Focus on Treatments, Monitoring, and Maintenance for Newly Diagnosed Multiple Myeloma Patients, With Updates, Friday, February 17, 2023, 12:00 PM-1:00 PM (ET), From Diagnosis to Prognosis: Understanding Multiple Myeloma (A Guide for Newly Diagnosed Patients), With Updates, Tuesday, January 24, 2023, 4:00 PM-5:00 PM (ET), Treatment Options for Patients Who Have Relapsed After Three or More Lines of Therapy, With an Update on Bispecific Antibodies, Friday, December 2, 2022, 1:00 PM-2:00 PM (ET), Wednesday, August 17, 2022, 1:00 PM2:00 PM (ET), Management of Patients Who Have Relapsed After One to Three Prior Lines of Therapy, Wednesday, July 13, 2022, 2:00 PM3:00 PM (ET), Focus on Treatments, Monitoring, and Maintenance for Newly Diagnosed Multiple Myeloma Patients, 2-M less than or equal to 3.5mg/L and albumin greater than or equal to 3.5 g/dL, 2-M greater than or equal to 5.5mg/L and either, Values Indicating a More Favorable Prognosis, Beta 2-microglobulin (2-microglobulin or 2-M).

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